Saturday, January 16, 2010

Is ziprasidone an effective atypical antipsychotic? Part 1

Almost every month there is a new antipsychotic drug, which is promoted to be the best. Atypical antipsychotics are now prescribed for many people as first line treatment. The question is how much difference do these drugs make and are the benefits worth it?

Remember, the atypical antipsychotics are prohibitively expensive. The latest atypical antipsychotic to be hyped up is ziprasidone. In this review, researchers looked to determine if ziprasidone was any better than other atypical anti psychotics like olanzapine or Risperidone.

Researchers compared ziprasidone with amisulpride, clozapine, olanzapine, quetiapine and Risperidone.

Results

What was observed was that Ziprasidone was slightly less efficacious antipsychotic drug than amisulpride, olanzapine and Risperidone. The only advantage of the drug was its low tendency to induce weight gain and associated adverse effects.

However, because the dug was not efficacious many individuals left the study.

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